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A signature enrichment design with Bayesian adaptive randomization
Clinical trials in the era of precision cancer medicine aim to identify and validate biomarker signatures which can guide the assignment of individually optimal treatments to patients. In this article, we propose a group sequential randomized phase II design, which updates the biomarker signature as...
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| I publikationen: | J Appl Stat |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8132854/ https://ncbi.nlm.nih.gov/pubmed/34024982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2020.1757048 |
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