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ACE2 Deficiency in Whole Body or Bone Marrow-Derived Cells Increases Atherosclerosis in LDL Receptor −/− Mice
OBJECTIVE: The renin-angiotensin system (RAS) contributes to atherosclerotic lesion formation. Angiotensin converting enzyme 2 (ACE2) catabolizes angiotensin II (AngII) to angiotensin-(1–7) (Ang-(1–7)) to limit effects of the RAS. The purpose of this study was to define the role of ACE2 in atheroscl...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086633/ https://ncbi.nlm.nih.gov/pubmed/21252069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.221614 |
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