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Mas receptor deficiency augments angiotensin II-induced atherosclerosis and aortic aneurysm ruptures in hypercholesterolemic male mice

OBJECTIVE: Previous studies demonstrated that deficiency of angiotensin converting enzyme 2 (ACE2) augmented angiotensin II-induced atherosclerosis and abdominal aortic aneurysm (AAA) formation in hypercholesterolemic mice. Effects of ACE2 deficiency could arise from increased concentrations of its...

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Bibliografiske detaljer
Udgivet i:J Vasc Surg
Main Authors: Stegbauer, Johannes, Thatcher, Sean E., Yang, Guang, Bottermann, Katharina, Rump, Lars Christian, Daugherty, Alan, Cassis, Lisa A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728232/
https://ncbi.nlm.nih.gov/pubmed/30850299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2018.11.045
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