Multivalent Smallpox DNA Vaccine Delivered by Intradermal Electroporation Drives Protective Immunity in Nonhuman Primates Against Lethal Monkeypox Challenge

The threat of a smallpox-based bioterrorist event or a human monkeypox outbreak has heightened the importance of new, safe vaccine approaches for these pathogens to complement older poxviral vaccine platforms. As poxviruses are large, complex viruses, they present technological challenges for simple...

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Dettagli Bibliografici
Autori principali: Hirao, Lauren A., Draghia-Akli, Ruxandra, Prigge, Jonathan T., Yang, Maria, Satishchandran, Abhishek, Wu, Ling, Hammarlund, Erika, Khan, Amir S., Babas, Tahar, Rhodes, Lowrey, Silvera, Peter, Slifka, Mark, Sardesai, Niranjan Y., Weiner, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086429/
https://ncbi.nlm.nih.gov/pubmed/21148501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq017
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