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Multivalent Smallpox DNA Vaccine Delivered by Intradermal Electroporation Drives Protective Immunity in Nonhuman Primates Against Lethal Monkeypox Challenge

The threat of a smallpox-based bioterrorist event or a human monkeypox outbreak has heightened the importance of new, safe vaccine approaches for these pathogens to complement older poxviral vaccine platforms. As poxviruses are large, complex viruses, they present technological challenges for simple...

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Dades bibliogràfiques
Autors principals: Hirao, Lauren A., Draghia-Akli, Ruxandra, Prigge, Jonathan T., Yang, Maria, Satishchandran, Abhishek, Wu, Ling, Hammarlund, Erika, Khan, Amir S., Babas, Tahar, Rhodes, Lowrey, Silvera, Peter, Slifka, Mark, Sardesai, Niranjan Y., Weiner, David B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086429/
https://ncbi.nlm.nih.gov/pubmed/21148501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq017
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