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Electroporation for the Delivery of DNA-based Vaccines and Immunotherapeutics: Current Clinical Developments

Electroporation (EP) has been used in basic research for the past 25 years to aid in the transfer of DNA into cells in vitro. EP in vivo enhances transfer of DNA vaccines and therapeutic plasmids to the skin, muscle, tumors, and other tissues resulting in high levels of expression, often with serolo...

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Detalhes bibliográficos
Main Authors: Bodles-Brakhop, Angela M, Heller, Richard, Draghia-Akli, Ruxandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835112/
https://ncbi.nlm.nih.gov/pubmed/19223870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.5
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