Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

DNA vaccines are a promising technology. Historically, however, the ability of DNA vaccines to induce high response rates and strong immune responses, especially antibody responses, in non-human primates and human clinical trials has proven suboptimal. Here, we performed a pilot study in rhesus maca...

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Vydáno v:Vaccine
Hlavní autoři: Hirao, Lauren A., Wu, Ling, Khan, Amir S., Hokey, David A., Yan, Jian, Dai, Anlan, Betts, Michael R., Draghia-Akli, Ruxandra, Weiner, David B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477809/
https://ncbi.nlm.nih.gov/pubmed/18430495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.02.036
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