Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation

We used optimized DNA expression vectors to compare two gene delivery methodologies in rhesus macaques, namely direct DNA injection and in vivo adaptive constant-current electroporation via the intramuscular route. The use of in vivo electroporation increased levels of gene expression and immune res...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Rosati, Margherita, Valentin, Antonio, Jalah, Rashmi, Patel, Vainav, von Gegerfelt, Agneta, Bergamaschi, Cristina, Alicea, Candido, Weiss, Deborah, Treece, Jim, Pal, Ranajit, Markham, Philip, Marques, Ernesto T. A., August, J. Thomas, Khan, Amir, Draghia-Akli, Ruxandra, Felber, Barbara K., Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263013/
https://ncbi.nlm.nih.gov/pubmed/18468743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.03.090
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