Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation

We used optimized DNA expression vectors to compare two gene delivery methodologies in rhesus macaques, namely direct DNA injection and in vivo adaptive constant-current electroporation via the intramuscular route. The use of in vivo electroporation increased levels of gene expression and immune res...

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Dettagli Bibliografici
Pubblicato in:Vaccine
Autori principali: Rosati, Margherita, Valentin, Antonio, Jalah, Rashmi, Patel, Vainav, von Gegerfelt, Agneta, Bergamaschi, Cristina, Alicea, Candido, Weiss, Deborah, Treece, Jim, Pal, Ranajit, Markham, Philip, Marques, Ernesto T. A., August, J. Thomas, Khan, Amir, Draghia-Akli, Ruxandra, Felber, Barbara K., Pavlakis, George N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263013/
https://ncbi.nlm.nih.gov/pubmed/18468743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.03.090
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