DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge

Optimized plasmid DNAs encoding the majority of SIVmac239 proteins and delivered by electroporation (EP) elicited strong immune responses in rhesus macaques. Vaccination decreased viremia in both the acute and chronic phases of infection after challenge with pathogenic SIVmac251. Two groups of macaq...

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書誌詳細
主要な著者: Rosati, Margherita, Bergamaschi, Cristina, Valentin, Antonio, Kulkarni, Viraj, Jalah, Rashmi, Alicea, Candido, Patel, Vainav, von Gegerfelt, Agneta S., Montefiori, David C., Venzon, David J., Khan, Amir S., Draghia-Akli, Ruxandra, Van Rompay, Koen K. A., Felber, Barbara K., Pavlakis, George N.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734879/
https://ncbi.nlm.nih.gov/pubmed/19717425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902628106
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