DNA Vaccines Expressing Different Forms of Simian Immunodeficiency Virus Antigens Decrease Viremia upon SIVmac251 Challenge

We have tested the efficacy of DNA immunization as a single vaccination modality for rhesus macaques followed by highly pathogenic SIVmac251 challenge. To further improve immunogenicity of the native proteins, we generated expression vectors producing fusion of the proteins Gag and Env to the secret...

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Detalhes bibliográficos
Main Authors: Rosati, Margherita, von Gegerfelt, Agneta, Roth, Patricia, Alicea, Candido, Valentin, Antonio, Robert-Guroff, Marjorie, Venzon, David, Montefiori, David C., Markham, Phil, Felber, Barbara K., Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143718/
https://ncbi.nlm.nih.gov/pubmed/15956591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8480-8492.2005
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