DNA Vaccines Expressing Different Forms of Simian Immunodeficiency Virus Antigens Decrease Viremia upon SIVmac251 Challenge

We have tested the efficacy of DNA immunization as a single vaccination modality for rhesus macaques followed by highly pathogenic SIVmac251 challenge. To further improve immunogenicity of the native proteins, we generated expression vectors producing fusion of the proteins Gag and Env to the secret...

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Bibliografiset tiedot
Päätekijät: Rosati, Margherita, von Gegerfelt, Agneta, Roth, Patricia, Alicea, Candido, Valentin, Antonio, Robert-Guroff, Marjorie, Venzon, David, Montefiori, David C., Markham, Phil, Felber, Barbara K., Pavlakis, George N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2005
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143718/
https://ncbi.nlm.nih.gov/pubmed/15956591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8480-8492.2005
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