Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaques

The New York City Board of Health (NYCBH) vaccinia virus is the currently licensed vaccine for use in the US against smallpox. The vaccine under investigation in this study has been attenuated by deletion of the innate immune evasion gene, E3L, and shown to be protective in homologous virus mouse ch...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Denzler, Karen L., Babas, Tahar, Rippeon, Amy, Huynh, Trung, Fukushima, Nobuko, Rhodes, Lowrey, Silvera, Peter M., Jacobs, Bertram L.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001690/
https://ncbi.nlm.nih.gov/pubmed/22001879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.135
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