The attenuated NYCBH vaccinia virus deleted for the immune evasion gene, E3L, completely protects mice against heterologous challenge with ectromelia virus

The New York City Board of Health (NYCBH) vaccinia virus (VACV) vaccine strain was deleted for the immune evasion gene, E3L, and tested for its pathogenicity and ability to protect mice from heterologous challenge with ectromelia virus (ECTV). NYCBHΔE3L was found to be highly attenuated for pathogen...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Denzler, Karen L, Schriewer, Jill, Parker, Scott, Werner, Chas, Hartzler, Hollyce, Hembrador, Ed, Huynh, Trung, Holechek, Susan, Buller, RM, Jacobs, Bertram L
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001685/
https://ncbi.nlm.nih.gov/pubmed/21983358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.108
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