Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum

We have previously shown that overexpression of the Glud1 (glutamate dehydrogenase 1) gene in neurons of C57BL/6 mice results in increased depolarization-induced glutamate release that eventually leads to selective neuronal injury and cell loss by 12 months of age. However, it is known that isogenic...

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Detalhes bibliográficos
Main Authors: Hascup, Kevin N, Bao, Xiaodong, Hascup, Erin R, Hui, Dongwei, Xu, Wenhao, Pomerleau, Francois, Huettl, Peter, Michaelis, Mary L, Michaelis, Elias K, Gerhardt, Greg A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Neurochemistry 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086280/
https://ncbi.nlm.nih.gov/pubmed/21446915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110005
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