Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum

We have previously shown that overexpression of the Glud1 (glutamate dehydrogenase 1) gene in neurons of C57BL/6 mice results in increased depolarization-induced glutamate release that eventually leads to selective neuronal injury and cell loss by 12 months of age. However, it is known that isogenic...

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Hlavní autoři: Hascup, Kevin N, Bao, Xiaodong, Hascup, Erin R, Hui, Dongwei, Xu, Wenhao, Pomerleau, Francois, Huettl, Peter, Michaelis, Mary L, Michaelis, Elias K, Gerhardt, Greg A
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Neurochemistry 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086280/
https://ncbi.nlm.nih.gov/pubmed/21446915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110005
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