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S-nitrosylation from GSNOR Deficiency Impairs DNA Repair and Promotes Hepatocarcinogenesis
Human hepatocellular carcinoma is associated with elevated expression of inducible nitric oxide synthase (iNOS), but the role of nitric oxide in the pathogenesis of hepatocellular carcinoma remains unknown. Here we show that the abundance and activity of S-nitrosoglutathione reductase (GSNOR), a pro...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085984/ https://ncbi.nlm.nih.gov/pubmed/20371487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000328 |
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