Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice

OBJECTIVE: Cyclophilin A (CyPA, encoded by Ppia) is a pro-inflammatory protein secreted in response to oxidative stress in mice and humans. We recently demonstrated that CyPA increased angiotensin II (AngII)-induced reactive oxygen species (ROS) production in the aortas of Apoe(−/−) mice. In this st...

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Hlavní autoři: Satoh, Kimio, Nigro, Patrizia, Zeidan, Asad, Soe, Nwe Nwe, Jaffré, Fabrice, Oikawa, Masayoshi, O’Dell, Michael R., Cui, Zhaoqiang, Menon, Prashanthi, Lu, Yan, Mohan, Amy, Yan, Chen, Blaxall, Burns C., Berk, Bradford C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085960/
https://ncbi.nlm.nih.gov/pubmed/21330604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.214601
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