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Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E–deficient mice

Cyclophilin A (CyPA; encoded by Ppia) is a ubiquitously expressed protein secreted in response to inflammatory stimuli. CyPA stimulates vascular smooth muscle cell migration and proliferation, endothelial cell adhesion molecule expression, and inflammatory cell chemotaxis. Given these activities, we...

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Hlavní autoři: Nigro, Patrizia, Satoh, Kimio, O'Dell, Michael R., Soe, Nwe Nwe, Cui, Zhaoqiang, Mohan, Amy, Abe, Jun-ichi, Alexis, Jeffrey D., Sparks, Janet D., Berk, Bradford C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023134/
https://ncbi.nlm.nih.gov/pubmed/21173104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101174
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