Cyclophilin A enhances vascular oxidative stress and development of angiotensin II-induced aortic aneurysms

Inflammation and oxidative stress are pathogenic mediators of many diseases, but therapeutic targets remain elusive. In the vasculature, abdominal aortic aneurysm (AAA) formation critically involves inflammaton and matrix degradation. Cyclophilin A (CyPA, encoded by Ppia) is highly expressed in vasc...

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Detaylı Bibliyografya
Asıl Yazarlar: Satoh, Kimio, Nigro, Patrizia, Matoba, Tetsuya, O'Dell, Michael R., Cui, Zhaoqiang, Shi, Xi, Mohan, Amy, Yan, Chen, Abe, Jun-ichi, Illig, Karl A., Berk, Bradford C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704983/
https://ncbi.nlm.nih.gov/pubmed/19430489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1958
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