A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma: A Phase II Trial of Safety, Efficacy, and Immune Activation

PURPOSE: Surgical resection provides the only possibility of cure for pancreas cancer. A standard adjuvant approach has not been established. We tested the safety and efficacy of a granulocyte-macrophage colony-stimulating factor (GM-CSF)-based immunotherapy administered in patients with resected pa...

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Detalhes bibliográficos
Main Authors: Lutz, Eric, Yeo, Charles J., Lillemoe, Keith D., Biedrzycki, Barbara, Kobrin, Barry, Herman, Joseph, Sugar, Elizabeth, Piantadosi, Steven, Cameron, John L., Solt, Sara, Onners, Beth, Tartakovsky, Irena, Choi, Miri, Sharma, Rajni, Illei, Peter B., Hruban, Ralph H., Abrams, Ross A., Le, Dung, Jaffee, Elizabeth, Laheru, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085934/
https://ncbi.nlm.nih.gov/pubmed/21217520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e3181fd271c
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