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A Safety and Feasibility Study of an Allogeneic Colon Cancer Cell Vaccine Administered with a Granulocyte–Macrophage Colony Stimulating Factor–Producing Bystander Cell Line in Patients with Metastatic Colorectal Cancer

BACKGROUND: Despite recent advances in earlier detection and improvements in chemotherapy, the 5-year survival rate of patients with metastatic colorectal carcinoma remains poor. Immunotherapy is a potentially effective therapeutic approach to the treatment of colorectal carcinoma. Preclinical studi...

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Main Authors: Zheng, Lei, Edil, Barish H., Soares, Kevin C., El-Shami, Khaled, Uram, Jennifer N., Judkins, Carol, Zhang, Zhe, Onners, Beth, Laheru, Daniel, Pardoll, Drew, Jaffee, Elizabeth M., Schulick, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192092/
https://ncbi.nlm.nih.gov/pubmed/24943235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-3844-x
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