Targeting NFκB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2

Resistance to chemotherapy remains a significant obstacle in the treatment of hormone-independent breast cancer. Recent evidence suggests that altered sphingolipid signaling through increased sphingosine kinase activity may be an important mediator of breast cancer drug resistance. Sphingosine kinas...

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Detalhes bibliográficos
Main Authors: Antoon, James W, White, Martin D, Slaughter, Evelyn M, Driver, Jennifer L, Khalili, Hafez S, Elliott, Steven, Smith, Charles D, Burow, Matthew E, Beckman, Barbara S
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084971/
https://ncbi.nlm.nih.gov/pubmed/21307639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.7.14903
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