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Antiestrogenic Effects of the Novel Sphingosine Kinase-2 Inhibitor ABC294640
Alterations in sphingolipid metabolism have been shown to contribute to the development of endocrine resistance and breast cancer tumor survival. Sphingosine kinase (SK), in particular, is overexpressed in breast cancer and is a promising target for breast cancer drug development. In this study, we...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Endocrine Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954724/ https://ncbi.nlm.nih.gov/pubmed/20861237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0420 |
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