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Antiestrogenic Effects of the Novel Sphingosine Kinase-2 Inhibitor ABC294640

Alterations in sphingolipid metabolism have been shown to contribute to the development of endocrine resistance and breast cancer tumor survival. Sphingosine kinase (SK), in particular, is overexpressed in breast cancer and is a promising target for breast cancer drug development. In this study, we...

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Bibliografische gegevens
Hoofdauteurs: Antoon, James W., White, Martin D., Meacham, William D., Slaughter, Evelyn M., Muir, Shannon E., Elliott, Steven, Rhodes, Lyndsay V., Ashe, Hasina B., Wiese, Thomas E., Smith, Charles D., Burow, Matthew E., Beckman, Barbara S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Endocrine Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954724/
https://ncbi.nlm.nih.gov/pubmed/20861237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0420
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