Antiestrogenic Effects of the Novel Sphingosine Kinase-2 Inhibitor ABC294640

Alterations in sphingolipid metabolism have been shown to contribute to the development of endocrine resistance and breast cancer tumor survival. Sphingosine kinase (SK), in particular, is overexpressed in breast cancer and is a promising target for breast cancer drug development. In this study, we...

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Main Authors: Antoon, James W., White, Martin D., Meacham, William D., Slaughter, Evelyn M., Muir, Shannon E., Elliott, Steven, Rhodes, Lyndsay V., Ashe, Hasina B., Wiese, Thomas E., Smith, Charles D., Burow, Matthew E., Beckman, Barbara S.
格式: Artigo
語言:Inglês
出版: The Endocrine Society 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954724/
https://ncbi.nlm.nih.gov/pubmed/20861237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0420
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