Tumor-Associated Macrophages Recruit CCR6(+) Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice

BACKGROUND: Tumor-associated macrophages (TAMs) remodel the colorectal cancer (CRC) microenvironment. Yet, findings on the role of TAMs in CRC seem to be contradictory compared with other cancers. FoxP3(+) regulatory T (Treg)-cells dominantly infiltrate CRC. However, the underlying molecular mechani...

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Main Authors: Liu, Jinlin, Zhang, Ning, Li, Qun, Zhang, Weiwei, Ke, Fang, Leng, Qibin, Wang, Hong, Chen, Jinfei, Wang, Honglin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084880/
https://ncbi.nlm.nih.gov/pubmed/21559338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019495
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