Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis

BACKGROUND: Regulatory T cells (Tregs) are highly prevalent in tumor tissue and can suppress effective anti-tumor immune responses. However, the source of the increased tumor-infiltrating Tregs and their contribution to cancer progression remain poorly understood. METHODOLOGY/PRINCIPAL FINDING: We h...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Kang-Jie, Lin, Sheng-Zhang, Zhou, Lin, Xie, Hai-Yang, Zhou, Wu-Hua, Taki-Eldin, Ahmed, Zheng, Shu-Sen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173477/
https://ncbi.nlm.nih.gov/pubmed/21935436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024671
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