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Tumor-Associated Macrophages Recruit CCR6(+) Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice
BACKGROUND: Tumor-associated macrophages (TAMs) remodel the colorectal cancer (CRC) microenvironment. Yet, findings on the role of TAMs in CRC seem to be contradictory compared with other cancers. FoxP3(+) regulatory T (Treg)-cells dominantly infiltrate CRC. However, the underlying molecular mechani...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084880/ https://ncbi.nlm.nih.gov/pubmed/21559338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019495 |
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