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Replacement of invariant bZip residues within the basic region of the yeast transcriptional activator GCN4 can change its DNA binding specificity.

Two residues are invariant in all bZip basic regions: asparagine -18 and arginine -10 (we define the first leucine of the leucine zipper of GCN4 as +1). X-ray structures of two specific GCN4-DNA complexes (Ellenberger et al., Cell, 71, 1223-1237, 1992; König & Richmond, J. Mol. Biol., 233, 139-1...

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Detaylı Bibliyografya
Asıl Yazarlar: Suckow, M, Schwamborn, K, Kisters-Woike, B, von Wilcken-Bergmann, B, Müller-Hill, B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1994
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC308472/
https://ncbi.nlm.nih.gov/pubmed/7971270
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