Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding.

Yeast GCN4 and the Jun oncoprotein are transcriptional activators that bind DNA via a bZIP domain consisting of a leucine zipper dimerization element and an adjacent basic region that directly contacts DNA. Two highly conserved alanines (Ala-238 and Ala-239 in GCN4) and an invariant asparagine (Asn-...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Pu, W T, Struhl, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.4918-4926.1991
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