Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding.
Yeast GCN4 and the Jun oncoprotein are transcriptional activators that bind DNA via a bZIP domain consisting of a leucine zipper dimerization element and an adjacent basic region that directly contacts DNA. Two highly conserved alanines (Ala-238 and Ala-239 in GCN4) and an invariant asparagine (Asn-...
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| 發表在: | Mol Cell Biol |
|---|---|
| Principais autores: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
1991
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.4918-4926.1991 |
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