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Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair
We have previously demonstrated that double-strand breaks (DSBs) in regions near telomeres are much more likely to result in large deletions, gross chromosome rearrangements, and chromosome instability than DSBs at interstitial sites within chromosomes. In the present study, we investigated whether...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084351/ https://ncbi.nlm.nih.gov/pubmed/21466975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.03.001 |
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