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Synthesis of 4′-aminopantetheine and derivatives to probe aminoglycoside N-6′-acetyltransferase
A convenient synthesis of 4′-aminopantetheine from commercial D-pantethine is reported. The amino group was introduced by reductive amination in order to avoid substitution at a sterically congested position. Derivatives of 4′-aminopantetheine were also prepared to evaluate the effect of O-to-N subs...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084192/ https://ncbi.nlm.nih.gov/pubmed/21225062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob01018a |
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