A carregar...

Synthesis and Use of Sulfonamide-, Sulfoxide-, or Sulfone-containing Aminoglycoside-CoA Bisubstrates as Mechanistic Probes for Aminoglycoside N-6′-Acetyltransferase

Aminoglycoside-coenzyme A conjugates are challenging synthetic targets because of the wealth of functional groups and high polarity of the starting materials. We previously reported a one-pot synthesis of amide-linked aminoglycoside-CoA bisubstrates. These molecules are nanomolar inhibitors of amino...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gao, Feng, Yan, Xuxu, Zahr, Omar, Larsen, Aaron, Vong, Kenward, Auclair, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084191/
https://ncbi.nlm.nih.gov/pubmed/18805003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.09.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!