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Cargo binding activates myosin VIIA motor function in cells

Myosin VIIA, thought to be involved in human auditory function, is a gene responsible for human Usher syndrome type 1B, which causes hearing and visual loss. Recent studies have suggested that it can move processively if it forms a dimer. Nevertheless, it exists as a monomer in vitro, unlike the wel...

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書目詳細資料
Main Authors: Sakai, Tsuyoshi, Umeki, Nobuhisa, Ikebe, Reiko, Ikebe, Mitsuo
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084129/
https://ncbi.nlm.nih.gov/pubmed/21482763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009188108
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