Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors

National Institutes of Health (NIH)-sponsored screening centers provide academic researchers with a special opportunity to pursue small-molecule probes for protein targets that are outside the current interest of, or beyond the standard technologies employed by, the pharmaceutical industry. Here, we...

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Detalhes bibliográficos
Main Authors: Bachovchin, Daniel A., Mohr, Justin T., Speers, Anna E., Wang, Chu, Berlin, Jacob M., Spicer, Timothy P., Fernandez-Vega, Virneliz, Chase, Peter, Hodder, Peter S., Schürer, Stephan C., Nomura, Daniel K., Rosen, Hugh, Fu, Gregory C., Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084096/
https://ncbi.nlm.nih.gov/pubmed/21398589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015248108
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