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Chemistry of mycolactones, the causative toxins of Buruli ulcer

Buruli ulcer is a severe and devastating skin disease caused by Mycobacterium ulcerans infection, yet it is one of the most neglected diseases. The causative toxin, referred to as mycolactone A/B, was isolated and characterized as a polyketide-derived macrolide in 1999. The current status of the myc...

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Autor principal: Kishi, Yoshito
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084064/
https://ncbi.nlm.nih.gov/pubmed/21383136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015252108
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