Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer

Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model. In order to elucidate the mechanism of this nerve damage, we t...

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Bibliographic Details
Published in:PLoS Negl Trop Dis
Main Authors: En, Junichiro, Kitamoto, Sho, Kawashima, Akira, Yonezawa, Suguru, Kishi, Yoshito, Ishii, Norihisa, Goto, Masamichi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559071/
https://ncbi.nlm.nih.gov/pubmed/28783752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005834
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