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MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells
Chromosome-wide inactivation is an epigenetic signature of sex chromosomes. The mechanism by which the chromosome-wide domain is recognized and gene silencing is induced remains unclear. Here we identify an essential mechanism underlying the recognition of the chromosome-wide domain in the male germ...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084029/ https://ncbi.nlm.nih.gov/pubmed/21536735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2030811 |
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