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MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells

Chromosome-wide inactivation is an epigenetic signature of sex chromosomes. The mechanism by which the chromosome-wide domain is recognized and gene silencing is induced remains unclear. Here we identify an essential mechanism underlying the recognition of the chromosome-wide domain in the male germ...

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Bibliografiska uppgifter
Huvudupphovsmän: Ichijima, Yosuke, Ichijima, Misako, Lou, Zhenkun, Nussenzweig, André, Camerini-Otero, R. Daniel, Chen, Junjie, Andreassen, Paul R., Namekawa, Satoshi H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084029/
https://ncbi.nlm.nih.gov/pubmed/21536735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2030811
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