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RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids

Sex chromosomes are uniquely subject to chromosome-wide silencing during male meiosis, and silencing persists into post-meiotic spermatids. Against this background, a select set of sex chromosome-linked genes escapes silencing and is activated in post-meiotic spermatids. Here, we identify a novel me...

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Detalhes bibliográficos
Main Authors: Sin, Ho-Su, Barski, Artem, Zhang, Fan, Kartashov, Andrey V., Nussenzweig, Andre, Chen, Junjie, Andreassen, Paul R., Namekawa, Satoshi H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533078/
https://ncbi.nlm.nih.gov/pubmed/23249736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.202713.112
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