CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice

Expression of the transmembrane glycoprotein CD98 (encoded by SLC3A2) is increased in intestinal inflammatory conditions, such as inflammatory bowel disease (IBD), and in various carcinomas, yet its pathogenetic role remains unknown. By generating gain- and loss-of-function mouse models with genetic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nguyen, Hang Thi Thu, Dalmasso, Guillaume, Torkvist, Leif, Halfvarson, Jonas, Yan, Yutao, Laroui, Hamed, Shmerling, Doron, Tallone, Tiziano, D’Amato, Mauro, Sitaraman, Shanthi V., Merlin, Didier
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2011
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083801/
https://ncbi.nlm.nih.gov/pubmed/21490400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44631
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