CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice

Expression of the transmembrane glycoprotein CD98 (encoded by SLC3A2) is increased in intestinal inflammatory conditions, such as inflammatory bowel disease (IBD), and in various carcinomas, yet its pathogenetic role remains unknown. By generating gain- and loss-of-function mouse models with genetic...

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Detaylı Bibliyografya
Asıl Yazarlar: Nguyen, Hang Thi Thu, Dalmasso, Guillaume, Torkvist, Leif, Halfvarson, Jonas, Yan, Yutao, Laroui, Hamed, Shmerling, Doron, Tallone, Tiziano, D’Amato, Mauro, Sitaraman, Shanthi V., Merlin, Didier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083801/
https://ncbi.nlm.nih.gov/pubmed/21490400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44631
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