CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice

Expression of the transmembrane glycoprotein CD98 (encoded by SLC3A2) is increased in intestinal inflammatory conditions, such as inflammatory bowel disease (IBD), and in various carcinomas, yet its pathogenetic role remains unknown. By generating gain- and loss-of-function mouse models with genetic...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nguyen, Hang Thi Thu, Dalmasso, Guillaume, Torkvist, Leif, Halfvarson, Jonas, Yan, Yutao, Laroui, Hamed, Shmerling, Doron, Tallone, Tiziano, D’Amato, Mauro, Sitaraman, Shanthi V., Merlin, Didier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083801/
https://ncbi.nlm.nih.gov/pubmed/21490400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44631
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky