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Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation(†)

Nucleoside Monophosphate Kinases (NMPKs) family are key enzymes in nucleotide metabolism. Bacterial UMPKs depart from the main superfamily of NMPKs. Having no eukaryotic counterparts they represent attractive therapeutic targets. They are regulated by GTP and UTP, while showing different mechanisms...

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Bibliografiske detaljer
Main Authors: Labesse, Gilles, Benkali, Khaled, Salard-Arnaud, Isabelle, Gilles, Anne-Marie, Munier-Lehmann, Hélène
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082897/
https://ncbi.nlm.nih.gov/pubmed/21149268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1250
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