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The translational repressor 4E-BP called to order by eIF4E: new structural insights by SAXS
eIF4E binding protein (4E-BP) inhibits translation of capped mRNA by binding to the initiation factor eIF4E and is known to be mostly or completely unstructured in both free and bound states. Using small angle X-ray scattering (SAXS), we report here the analysis of 4E-BP structure in solution, which...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082885/ https://ncbi.nlm.nih.gov/pubmed/21183464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1306 |
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