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Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC

Multidrug efflux pumps adversely affect both the clinical effectiveness of existing antibiotics and the discovery process to find new ones. In this study, we reconstituted and characterized by surface plasmon resonance the assembly of AcrAB-TolC, the archetypal multidrug efflux pump from Escherichia...

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Main Authors: Tikhonova, Elena B., Yamada, Yoichi, Zgurskaya, Helen I.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082741/
https://ncbi.nlm.nih.gov/pubmed/21513882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.02.011
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