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Agonist-Directed Desensitization of the β(2)-Adrenergic Receptor

The β(2)-adrenergic receptor (β(2)AR) agonists with reduced tachyphylaxis may offer new therapeutic agents with improved tolerance profile. However, receptor desensitization assays are often inferred at the single signaling molecule level, thus ligand-directed desensitization is poorly understood. H...

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מידע ביבליוגרפי
Main Authors: Goral, Vasiliy, Jin, Yan, Sun, Haiyan, Ferrie, Ann M., Wu, Qi, Fang, Ye
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082563/
https://ncbi.nlm.nih.gov/pubmed/21541288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019282
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