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Agonist-Directed Desensitization of the β(2)-Adrenergic Receptor

The β(2)-adrenergic receptor (β(2)AR) agonists with reduced tachyphylaxis may offer new therapeutic agents with improved tolerance profile. However, receptor desensitization assays are often inferred at the single signaling molecule level, thus ligand-directed desensitization is poorly understood. H...

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Bibliografische gegevens
Hoofdauteurs: Goral, Vasiliy, Jin, Yan, Sun, Haiyan, Ferrie, Ann M., Wu, Qi, Fang, Ye
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082563/
https://ncbi.nlm.nih.gov/pubmed/21541288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019282
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