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Label-free integrative pharmacology on-target of drugs at the β(2)-adrenergic receptor
We describe a label-free integrative pharmacology on-target (iPOT) method to assess the pharmacology of drugs at the β(2)-adrenergic receptor. This method combines dynamic mass redistribution (DMR) assays using an array of probe molecule-hijacked cells with similarity analysis. The whole cell DMR as...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216520/ https://ncbi.nlm.nih.gov/pubmed/22355552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00033 |
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