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Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family

BACKGROUND: In vitro pharmacology of ligands is typically assessed using a variety of molecular assays based on predetermined molecular events in living cells. Many ligands including opioid ligands pose the ability to bind more than one receptor, and can also provide distinct operational bias to act...

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Autori principali: Morse, Megan, Sun, Haiyan, Tran, Elizabeth, Levenson, Robert, Fang, Ye
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602246/
https://ncbi.nlm.nih.gov/pubmed/23497702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-17
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