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Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M(3) receptors
INTRODUCTION: Efficacy describes the property of a ligand that enables the receptor to change its behavior towards the host cell, while biased agonism defines the ability of a ligand to differentially activate some of the vectorial pathways over others mediated through the receptor. However, little...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858480/ https://ncbi.nlm.nih.gov/pubmed/23933114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vascn.2013.07.005 |
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